• César Vallejo, poet, lived in Trujillo from 1910 to 1917.
• Antenor Orrego, First Peruvian political philosopher, lived in Trujillo from 1910 to 1940.
• Víctor Raúl Haya de la Torre, political leader who founded the American Popular Revolutionary Alliance (APRA).1924.
• Teofilo Tinoco Caballero, lawyer and professor, born in Trujillo, lived from 1917 to 1994.
• Luis Banchero Rossi, chemical-industrial engineer(UNT,1950), He was the most important Peruvian businessman in s.XX. He lived in

Trujillo from 1940 to 1955.

• Milly Ahón Olguin, marinera dancer and Teacher, first dancer to dance with out shoes in a national setting . She is known as the Masters of Masters in marinera and tondero . Recognized Personality of peruvian Culture, ex director of Escuela nacional de Folklore Jose Maria Arguedas in Lima.
• Maria Julia Mantilla, Miss World 2004
• Henry Ian Cusick, Emmy-nominated actor.
• Teodoro Rivero Ayllón, writer and professor.
• Julio Cruzado Zavala, Senador, Politico, Secretario General de CTP
• Alejandro Aguilar Medina, research worker of the culture of Chimú
• Gerardo Chavez, artist of Trujillo.
• Eduardo Gonzalez Viaña, writer author of novel "Vallejo en los Infiernos".
• Pedro Azabache Bustamante, he was an Indigenist and Costumbrist painter who also founded School of fine arts Macedonio de La Torre in Trujillo.
• Gerardo Privat Dextre, fashion designer.[28]
• Guillermo Larco Cox, engineer and politician.
• Carlos Valderrama Herrera, musician.
• Victor Larco Herrera, politician and philanthropist.
• Teófilo Álvarez, classic musician.
• Pepe Alva, rock and pop musician.
• Víctor Felipe Calderón Valeriano, a master of marinera dance.
• Omar Forero, a film director in 2012 he directed the film Chicama chosen as the best film of 2012 by the "Peruvian Association of Cinematographic Press".[29]